Case 3. Unicameral bone cyst with rapid growth
Case first posted Mon, Nov 11, 2002; by John Hunter
This is a case from Mike Tuite (Michael Tuite <mjtuite@facstaff.wisc.edu>). He included the following clinical information:
6 year old boy who had a pelvis film done for right hip pain. The intertrochanteric lytic lesion was barely visisible on the inferior aspect of a KUB performed 8 months earlier. On MR, the lesion had several enhancing nodules within the fluid/myxoid material, as well as enhancing periostitis, but otherwise looked like a Simple Bone Cyst with thin enhancing lining. Pathology confirmed a UBC and the nodules were just benign fibrovascular tissue with occasional giant cells. We figured probably just an occult fx with early healing. p.s. they packed it with Wright Medical MIIG calcium sulfate, which completely resorbed in 4 weeks.
The question, ever see a UBC grow that fast? Pelvis as seen on KUB 8 months prior:

Initial KUB from 8 months earlier

Preop AP pelvis

Preop frogleg of both hips

Axial T1W images

Coronal T1W images

Axial T2W images

Coronal T2W images

Axial and sagittal T1W fat sat post Gd images

Coronal T1W fat sat post Gd images


Initially posted 11/12/02
I have never seen a simple cyst go this fast. About the only bone lesions that I usually see with this velocity are infections and aggressive, untreated metastases, which we know aren't happening here.
However, another thought occurs to me: to get this much bone removal so quickly means that osteoclasts have to be working hard. We know that this lesion is not a brown tumor, but could he have possibly have elevated PTH levels from occult renal or parathyroid disease?